Characterizing the association between complement-mediated TMA and cognitive dysfunction using MRI and neurocognitive assessment

This paper of the day explores the long-term neurocognitive effects of a rare and life-threatening blood disorder known as CM-TMA. Researchers used state-of-the-art imaging techniques as well as neurocognitive testing to assess patients with CM-TMA and healthy controls. The results show that in the brains of CM-TMA patients, there are great white matter changes along with impaired memory and concentration. These results highlight the long-term follow-up and even neurocognitive interventions necessary for patients with CM-TMA.